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Issue |
Title |
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No 1 (2025) |
Study of anxiolytic activity and possible side effects of the dipeptide ligand of the translocator protein TSPO — compound GD-102 in a wide range of doses in behavioral experiments using rats and mice |
Abstract
PDF (Rus)
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S. O. Kotel'nikova, O. A. Deeva, V. A. Kraineva, T. A. Gudasheva, T. A. Voronina, V. L. Dorofeev |
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No 1 (2025) |
Study of the possibility of using metformin by intranasal administration for the correction of behavioral and cognitive dysfunctions of rats |
Abstract
PDF (Rus)
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A. Z. Hafizova, I. I. Semina |
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No 1 (2025) |
The study of antiparkinsonian activity of the combination of ladasten with fabomotizole in paraquat-induced model of parkinsoian syndrome |
Abstract
PDF (Rus)
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V. E. Marievskii, İ. A. Lyubanskii, S. V. Shangin, L. F. Zainullina, V. L. Dorofeev |
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No 4 (2024) |
Involvement of TRK receptors in the nootropic effect of cycloprolylglycine |
Abstract
PDF (Rus)
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O. N. Vorontsova, A. G. Alyaeva, K. N. Koliasnikova, P. Yu. Povarnina, T. A. Gudasheva, V. L. Dorofeev |
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No 4 (2024) |
The cardiotropic properties of ZMEI-3 compound – a potential inhibitor of Epac proteins |
Abstract
PDF (Rus)
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S. A. Kryzhanovskii, G. V. Mokrov, I. B. Tsorin, E. O. Ionova, M. B. Vititnova, V. N. Stolyaruk, I. A. Miroshkina, A. V. Sorokina, A. D. Durnev |
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No 4 (2024) |
Нepatoprotective еffects of lithium ascorbate on a model of nonalcoholic fatty liver disease with iron overload |
Abstract
PDF (Rus)
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T. E. Bogacheva, A. G. Kalacheva, O. A. Gromova, I. Yu. Torshin, T. R. Grishina, A. A. Garanin |
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No 3 (2024) |
Synthesis and the antidepressant-like activity investigation of bis-(N-monosuccinyl-D-seryl-D-lysine) hexamethylenediamide, the DD-enantiomer of the BDNF dipeptide mimetic, compound GSB-106 |
Abstract
PDF (Rus)
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N. M. Sazonova, A. V. Tarasyuk, M. Yu. Filippova, M. V. Melnikova, D. M. Nikiforov, P. Yu. Povarnina, T. A. Gudasheva, V. L. Dorofeev |
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No 3 (2024) |
Effects of CAPAH, memantine, and rivastigmine on behavioral and cognitive functions of rats |
Abstract
PDF (Rus)
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D. O. Nikitin, I. I. Semina, A. V. Valeeva, A. V. Nikitina, A. Z. Khafizova, A. G. Ovchinnikova |
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No 3 (2024) |
Anticancer activity of tyrosine kinase TrkA receptors antagonist GK-1 in experiment on mice with mammary gland adenocarcinoma Ca755 |
Abstract
PDF (Rus)
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L. P. Kovalenko, P. Yu. Povarnina, R. V. Zhurikov, S. V. Alekseeva, L. G. Kolik, T. A. Gudasheva, A. D. Durnev, V. I. Dorofeev |
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No 3 (2024) |
Effect of cyclo-L-prolylglycine on pain response thresholds and morphine-induced analgesia in inbred BALB/c and C57Bl/6 mice |
Abstract
PDF (Rus)
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A. V. Nadorova, K. N. Koliasnikova, I. V. Chernyakova, L. G. Kolik |
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No 2 (2024) |
“Holiday heart” syndrome in rats: Features of microcirculation, functional state and anatomy of the heart |
Abstract
PDF (Rus)
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S. A. Kryzhanovskii, I. B. Tsorin, E. O. Ionova, M. B. Vititnova, S. A. Simonenko, L. G. Kolik |
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No 2 (2024) |
Behavioral features of Wistar rats in models of autism spectrum disorders induced by prenatal or postnatal administration of sodium valproate |
Abstract
PDF (Rus)
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E. V. Savinkova, I. G. Kapitsa, T. A. Voronina |
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No 2 (2024) |
Blood microcirculation under conditions of a translational model of alcohol cardiomyopathy in rats |
Abstract
PDF (Rus)
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S. A. Kryzhanovskii, I. B. Tsorin, E. O. Ionova, S. A. Simonenko, M. B. Vititnova |
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No 2 (2024) |
Experimental model of autism spectrum disorder induced by prenatal administration of propionic acid to Wistar rats |
Abstract
PDF (Rus)
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V. S. Boyarkin, I. G. Kapitsa, T. A. Voronina |
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No 2 (2024) |
Possible approaches to reproduction of endothelial dysfunction. searching for the optimal model |
Abstract
PDF (Rus)
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I. B. Tsorin, L. V. Kozhevnikova, S. A. Simonenko, I. F. Sukhanova, M. B. Vititnova, S. A. Kryzhanovskii |
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No 2 (2024) |
Experimental study of the anti-inflammatory activity of diclofenac in ultra-low doses on a model of acute carrageenan inflammation |
Abstract
PDF (Rus)
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O. A. Makhmudova, G. F. Avkhadieva, V. N. Khaziakhmetova, D. O. Nikitin, I. I. Semina |
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No 1 (2024) |
A study on the mnemotropic and antidepressant-like effects of the low-molecular-weight mimetic of nerve growth factor, dipeptide GK-2, in experimental ischemic stroke |
Abstract
PDF (Rus)
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P. Yu. Povarnina, N. M. Sazonova, D. M. Nikiforov, T. A. Gudasheva, V. L. Dorofeev |
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No 1 (2024) |
The possibility of calculating optimal doses in combined medicinal product (Working hypothesis) |
Abstract
PDF (Rus)
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I. B. Tsorin, S. A. Kryzhanovskii |
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No 3 (2023) |
Pharmacological activity of calcium lactate on a model of dysbiosis in rats |
Abstract
PDF (Rus)
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N. L. Polyuga, E. I. Trofimets, K. E. Borovkova, L. R. Nikiforova, Ju. V. Salmova, A. A. Peleshok, K. L. Kryshen, M. N. Makarova, A. M. Kolodkin, D. E. Mitereva, I. S. Kasatkina |
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No 3 (2023) |
Neuropeptide cyclo-L-prolylglycine counteracts scopolamine-induced long-term memory impairment in rats in the novel object recognition test |
Abstract
PDF (Rus)
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O. N. Vorontsova, A. G. Alyaeva, K. N. Koliasnikova, E. A. Valdman, P. Yu. Povarnina |
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No 3 (2023) |
Features of the compound ALM-802 antiarrhythmic action |
Abstract
PDF (Rus)
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V. V. Barchukov, V. P. Zinchenko, I. B. Tsorin, I. Yu. Teplov, V. N. Stolyaruk, M. B. Vititnova, G. V. Mokrov, S. A. Kryzhanovskii |
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No 3 (2023) |
Experimental investigation of the behavioral effects of new phosphorylated thiosemicarbazides |
Abstract
PDF (Rus)
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A. V. Nikitina, I. I. Semina, D. O. Nikitin, E. L. Gavrilova, I. A. Krutov, A. O. Isaeva |
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No 3 (2023) |
Antidepressant activity of the pyrrolo[1,2a][1,4]diazepine GMAL-24 in a forced swimming test in mice |
Abstract
PDF (Rus)
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A. O. Korolev, A. V. Volkova, Ya. S. Kozin, G. V. Mokrov, T. A. Voronina, T. S. Kalinina |
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No 3 (2023) |
Study of the relationship between the severity of alcoholic cardiomyopathy and the level of alcohol consumption in male and female rats in the model of “home drinking” |
Abstract
PDF (Rus)
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S. A. Kryzhanovskii, I. B. Tsorin, E. O. Ionova, V. V. Barchukov, V. N. Stolyaruk, M. B. Vititnova, L. G. Kolik, A. D. Durnev |
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No 2 (2023) |
Combined effect of fabomotizol and the compound ALM-802 on atrial depolarization in a translational model of alcoholic cardiomyopathy in rats |
Abstract
PDF (Rus)
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S. L. Smirnova, I. M. Roshchevskaya, V. V. Barchukov, I. B. Tsorin, S. A. Kryzhanovskii |
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No 2 (2023) |
Study of the antiarrhythmic activity of linear alkoxyphenylazalkanes in the model of reperfusion arrythmias in rats |
Abstract
PDF (Rus)
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V. V. Barchukov, V. N. Stolyaruk, I. B. Tsorin, M. B. Vititnova, S. А. Kryzhanovskii, T. Yu. Vorobieva, V. E. Biryukova, G. V. Mokrov |
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No 1 (2023) |
Validation of ELISA Test-system for Trastuzumab (Herceptin, Hertikad) quantitative determination in biological fluids |
Abstract
PDF (Rus)
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V. V. Pisarev, A. V. Ivanov |
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No 2 (2022) |
Effects of pantogam active on behavior and neuroreceptor spectrum in mouse model of attention deficit disorder |
Abstract
PDF (Rus)
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N. A. Sukhorukova, E. V. Vasileva, E. A. Kondrakhin, R. M. Salimov, G. I. Kovalev |
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No 2 (2022) |
The effect of fabomotizole on blood microcirculation in intact and ischemic myocardium |
Abstract
PDF (Rus)
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I. B. Tsorin, S. A. Simonenko, M. B. Vititnova, S. A. Kryzhanovskiy |
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No 1 (2022) |
The mimetic of the brain neurotrophic factor GSB-106 has neuroprotective and neuroregenerative effects in experimental ischemic stroke |
Abstract
PDF (Rus)
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P. Yu. Povarnina, T. A. Antipova, I. O. Logvinov, D. M. Nikiforov |
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No 1 (2022) |
Effect of the combination of mexidol and diclofenac sodium on exudative inflammation in rats after ten-day preventive oral administration |
Abstract
PDF (Rus)
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E. A. Ivanova, A. G. Vasilchuk, A. I. Matyushkin, T. A. Voronina |
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No 1 (2022) |
Study of diazepam effects on Ehrlich ascites carcinoma and anxiety responses in male SHK mice |
Abstract
PDF (Rus)
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T. S. Kalinina, A. A. Shimshirt, K. V. Lisitskaya, A. V. Volkova, N. V. Kudryashov |
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No 1 (2022) |
Selank effects on morphine-induced analgesia in vivo experiments |
Abstract
PDF (Rus)
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A. V. Nadorova, I. V. Chernyakova, L. G. Kolik |
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No 4 (2021) |
Study of the effect of the VEGF receptor blockade on the antiischemic activity of the compound GK-2 in a rat hind limb ischemia model |
Abstract
PDF (Rus)
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E. S. Pekeldina, I. A. Miroshkina, A. V. Sorokina, N. M. Sazonova, M. B. Vititnova, S. A. Kryzhanovskiy |
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No 4 (2021) |
Investigation of the fabomotizol dihydrochloride effect on the morphological picture of the heart left ventricle in rats with the subacute myocardial infarction |
Abstract
PDF (Rus)
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I. A. Miroshkina, A. V. Sorokina, I. B. Tsorin, V. N. Stolyaruk, M. B. Vititnova, S. A. Kryzhanovskiy, A. D. Durnev |
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No 4 (2021) |
To the possibility of detecting the "coronary theft" syndrome in small laboratory animals |
Abstract
PDF (Rus)
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I. B. Tsorin, S. A. Simonenko, M. B. Vititnova, S. A. Kryzhanovskiy |
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No 3 (2021) |
Gender differences in the formation of the epileptic system in male and female rats depending on the stage of the estrous cycle on the model of focal cobalt epilepsy |
Abstract
PDF (Rus)
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T. A. Voronina, S. A. Litvinova, Y. B. Filatova |
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No 3 (2021) |
Dynamics of the cardioelectric field of rats under chronic exposure to doxorubicin during atrial depolarization |
Abstract
PDF (Rus)
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S. L. Smirnova, O. V. Suslonova, I. M. Roshchevskaya |
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No 2 (2021) |
Antiarrhythmic properties of N-Deacetyllappaconitine Hydrochloride |
Abstract
PDF (Rus)
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S. A. Kryzhanovskii, M. S. Yunusov, I. B. Tsorin, V. V. Barchukov, E. I. Barchukova |
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No 2 (2021) |
Effect of ethylmethylhydroxypyridine succinate on the functional activity of the transporter P-glycoprotein in the blood-brain barrier of rats under normal conditions and under hypoxic hypoxia |
Abstract
PDF (Rus)
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P. Yu. Mylnikov, A. V. Shchulkin, I. V. Chernykh, E. N. Yakusheva |
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No 1 (2021) |
Evaluation of the antitumor activity of 2-[3-(2-chloroethyl)-3-nitrosoureido]-1,3-propanediol (chlonisol) in C57BL/6 mice with intracranially transplanted B16 melanoma |
Abstract
PDF (Rus)
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I. G. Murazov, A. N. Stukov, Iu. G. Zmitrichenko, A. O. Niuganen, G. V. Tochilnikov, D. Ch. Latipova, L. V. Filatova, T. Yu. Semiglazova |
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No 1 (2021) |
Comparative evaluation of echocardiographic characteristics of the heart left ventricle in female and male rats |
Abstract
PDF (Rus)
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E. O. Ionova, E. I. Barchukova, M. B. Vititnova, I. B. Tsorin, S. A. Kryzhanovskii |
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No 1 (2021) |
Cardioprotective effects of compound ALM-802 on subendocardial ischemia models |
Abstract
PDF (Rus)
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I. B. Tsorin, V. V. Barchukov, M. B. Vititnova, A. M. Likhosherstov, G. V. Mokrov, S. A. Kryzhanovskii |
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No 4 (2020) |
Effect of the compound GIZH -290 and levetiracetam on epileptic activity in rat brain structures on EEG models of bemegrid-induced seizures |
Abstract
PDF (Rus)
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T. A. Voronina, S. A. Litvinova, I. G. Kovalev |
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No 4 (2020) |
Effect of nerve growth factor dimeric mimetic GK-2 on microcirculation in skeletal muscle on the hind limb ischemia model in rats |
Abstract
PDF (Rus)
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I. B. Tsorin, A. O. Efimova, E. S. Pekeldina, M. B. Vititnova, S. A. Kryzhanovskii |
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No 3 (2020) |
Comparative study of the neuroprotective activity of lithium compounds and their effect on the course of experimental alloxan diabetes mellitus in rats |
Abstract
PDF (Rus)
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O. A. Nazarenko, V. I. Demidov, O. A. Gromova, E. L. Aleksakhina, I. Yu. Torshin |
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No 2 (2020) |
The in vitro neuroprotective activity of analogues of N-terminus substituted glyprolines |
Abstract
PDF (Rus)
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S. V. Nikolaev, I. O. Logvinov, K. N. Koliasnikova, E. A. Kuznetsova, P. I. Antipov, T. A. Antipova |
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No 2 (2020) |
Confirmation of validity of the developed translational model of chronic heart failure in rats |
Abstract
PDF (Rus)
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I. B. Tsorin, V. V. Barchukov, E. O. Ionova, V. N. Stolayruk, M. B. Vititnova, S. A. Kryzhanovskii |
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No 1 (2020) |
Screening study of nerve growth factor's and brain-derived neurotrophic factor's mimetics effects at the experimental depression model |
Abstract
PDF (Rus)
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A. G. Mezhlumyan, A. V. Tallerova, P. Yu. Povarnina, N. M. Sazonova, A. V. Tarasiuk, T. A. Gudasheva |
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No 1 (2020) |
Researches of the imidazole and indole derivatives cerebroprotective activity and its impact on effects of antidepressants |
Abstract
PDF (Rus)
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I. I. Abramets, T. O. Zayka, D. V. Evdokimov, Y. V. Kuznetsov, Y. V. Sidorova |
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No 4 (2019) |
Study of ALM-802 orto-alkoxi analogues cardiotropic activity |
Abstract
PDF (Rus)
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G. V. Mokrov, A. M. Likhosherstov, V. V. Barchukov, V. N. Stolyaruk, I. B. Tsorin, M. B. Vititnova, S. A. Kryzhanovskiy, T. A. Gudasheva |
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No 4 (2019) |
Antidepressant-like activity of the dipeptide mimetic of brain-derived neurotrophic factor GSB-106 in Porsolt test after intraperitoneal sub-chronically and chronically treatment in mice |
Abstract
PDF (Rus)
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A. V. Tallerova, P. Y. Povarnina, S. V. Minaev, T. A. Gudasheva, S. B. Seredenin |
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No 1 (2017) |
The effectiveness of lithium ascorbate on chronic alcohol intoxication model |
Abstract
PDF (Rus)
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K. V. Ostrenko, O. A. Gromova, I. S. Sardaryan, V. I. Demidov, N. Yu. Zhidomorov, I. Yu. Torshin, A. V. Pronin, V. A. Krivonogov, Yu. V. Karpunina |
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No 4 (2018) |
Cytoprotective properties of the nerve growth factor and brain derived neurotrophic factor dipeptidic mimetics, GK-2 AND GSB-106, in the model of oxidative stress in paramecium caudatum |
Abstract
PDF (Rus)
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O. V. Karpukhina, A. N. Inozemtsev, K. Z. Gumargalieva, P. Yu. Povarnina, T. A. Gudasheva |
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No 1 (2017) |
Novel 4-benzoylpyridine oxime derivative GIZH-298 with aticonvulsant activity |
Abstract
PDF (Rus)
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L. A. Zhmurenko, G. V. Mokrov, L. N. Nerobkova, S. A. Litvinova, I. O. Gaydukov, T. A. Voronina, T. A. Gudasheva |
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No 1 (2019) |
The influence of succinate-containing drugs on physical performance and recovery after exercise |
Abstract
PDF (Rus)
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S. V. Radko, A. D. Dulepov |
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No 3 (2017) |
Neuroprotective effect of L-cycloprolylglycine on models neuronal cells damage in vitro |
Abstract
PDF (Rus)
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S. V. Nikolaev, I. O. Logvinov, P. I. Antipov, K. N. Kolyasnikova, T. A. Antipova |
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No 1 (2019) |
Study of methoxy-group position influence on compound alm-802 cardiotropic activity |
Abstract
PDF (Rus)
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G. V. Mokrov, A. M. Likhosherstov, V. V. Barchukov, V. N. Stolyaruk, I. B. Tsorin, M. B. Vititnova, S. A. Kryzhanovskiy, T. A. Gudasheva |
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No 3 (2017) |
A study of neuroprotective effect stereospecificity of dipeptide mimetic of the Brain-derived neurotrophic factor GSB-106 on the model oxidative stress in the culture hippocampal cell line HT-22 |
Abstract
PDF (Rus)
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I. O. Logvinov, A. V. Tarasiuk, P. I. Antipov, T. A. Antipova |
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No 1 (2019) |
Effect of mexidol on physical and mental performance under stressogenic conditions in experiment |
Abstract
PDF (Rus)
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I. G. Kapitsa, E. A. Ivanova, T. A. Voronina |
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No 4 (2017) |
Neuroprotective and anticonvulsant effects of Cerebrolysin in the experiment |
Abstract
PDF (Rus)
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T. E. Bogacheva, A. G. Kalacheva, T. R. Grishina, O. A. Gromova, T. V. Surakova |
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No 2 (2019) |
Cardioelectric field on the body surface during atrial depolarization in rats with alcoholic cardiomyopathy |
Abstract
PDF (Rus)
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S. L. Smirnova, I. M. Roshchevskaya, I. B. Tsorin, V. N. Stolyaruk, M. B. Vititnova, L. G. Kolik, S. A. Kryzhanovskii |
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No 4 (2017) |
The study of the effects of magnesium orotate on the model of primary generalized convulsions in rats |
Abstract
PDF (Rus)
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A. G. Kalacheva, T. E. Bogacheva, O. A. Gromova, T. R. Grishina, V. I. Demidov |
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No 2 (2019) |
A comparative study of the anti-ischemic activity of trimetazidine and the compound ALM-802 under conditions of endothelial dysfunction |
Abstract
PDF (Rus)
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V. V. Barchukov, I. B. Tsorin, A. M. Likhosherstov, M. B. Vititnova, G. V. Mokrov, S. A. Kryzhanovskii |
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