The antifibrillatory activity study of the compound LMG-124 and lappaconitine hydrobromide on the reperfusion arrhythmias model
Abstract
The antifibrillatory activity comparative study of the compound LMG-124 and the reference drug Lappaconitine hydrobromide was performed on the model of reperfusion arrhythmias. Both drugs are shown to exhibit antiarrhythmic and antifibrillatory activity, but the compound LMG-124 realizes its effect in a significantly lower dose.
About the Authors
V. N. Stolyaruk
FSBI «Zakusov Institute of Pharmacology»
Russian Federation
Russian Federation
I. B. Tsorin
FSBI «Zakusov Institute of Pharmacology»
Russian Federation
Russian Federation
M. B. Vititnova
FSBI «Zakusov Institute of Pharmacology»
Russian Federation
Russian Federation
V. P. Gusev
FSBI «Zakusov Institute of Pharmacology»
Russian Federation
Russian Federation
Yu. I. Murinov
FSBIS «Ufa Institute of Chemistry of the Russian Academy of Sciences» (UIC RAS)
Russian Federation
Russian Federation
M. S. Yunusov
FSBIS «Ufa Institute of Chemistry of the Russian Academy of Sciences» (UIC RAS)
Russian Federation
Russian Federation
S. A. Kryzhanovskii
FSBI «Zakusov Institute of Pharmacology»
Russian Federation
Russian Federation
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Review
For citations:
Stolyaruk V.N., Tsorin I.B., Vititnova M.B., Gusev V.P., Murinov Yu.I., Yunusov M.S., Kryzhanovskii S.A. The antifibrillatory activity study of the compound LMG-124 and lappaconitine hydrobromide on the reperfusion arrhythmias model. Pharmacokinetics and Pharmacodynamics. 2017;(2):16-18. (In Russ.)
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