Isoform CYP1A2, as a part of the cytochrome P450 superfamily
Abstract
The role of cytochrome P450 isoforms CYP1A2 and in the metabolism of caffeine is described. Caffeine pharmacokinetics data in humans and laboratory animals are presented. Examples of drug-drug interactions of cubstrate marker caffeine with different drugs are given.
About the Authors
Y. G. Novickaya
FGBI «Institute of Pharmacology named after V.V. Zakusov» RAS
Russian Federation
Russian Federation
V. P. Zherdev
FGBI «Institute of Pharmacology named after V.V. Zakusov» RAS
Russian Federation
Russian Federation
A. O. Viglinskaya
FGBI «Institute of Pharmacology named after V.V. Zakusov» RAS
Russian Federation
Russian Federation
A. A. Litvin
FGBI «Institute of Pharmacology named after V.V. Zakusov» RAS
Russian Federation
Russian Federation
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Novickaya Y.G., Zherdev V.P., Viglinskaya A.O., Litvin A.A. Isoform CYP1A2, as a part of the cytochrome P450 superfamily. Pharmacokinetics and Pharmacodynamics. 2014;(1):4-13. (In Russ.)
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