Comparative evaluation of echocardiographic characteristics of the heart left ventricle in female and male rats
https://doi.org/10.37489/2587-7836-2021-1-14-17
Abstract
The aim of the present study is a comparative assessment of the echocardiographic characteristics in female and male mongrel rats. In experiments on anesthetized rats (ketamine 100 mg / kg, iv), it was shown that in female rats, the size and volume of the left ventricle are smaller than in males, but compared with males, their left ventricular ejection fraction, which characterizes its inotropic function, is statistically significantly higher.
About the Authors
E. O. Ionova
FSBI “Zakusov Institute of Pharmacology”
Russian Federation
Russian Federation
Ionova Ekaterina O., Junior Research Scientist of Laboratory of Pharmacological Screening
SPIN code: 5042-1952
Moscow
E. I. Barchukova
FSBI “Zakusov Institute of Pharmacology”
Russian Federation
Russian Federation
Barchukov Vladimir V., Research scientist of laboratory of pharmacological screening
SPIN code: 6743-4280
Moscow
M. B. Vititnova
FSBI “Zakusov Institute of Pharmacology”
Russian Federation
Russian Federation
Vititnova Marina B., PhD Biological Sci., Senior researcher scientist of laboratory of pharmacological screening
SPIN code: 1901-8919
Moscow
I. B. Tsorin
FSBI “Zakusov Institute of Pharmacology”
Russian Federation
Russian Federation
Tsorin Iosif B., Dr. Sci. Biological, Leading researcher of laboratory of pharmacological screening
SPIN code: 4015-3025
Moscow
S. A. Kryzhanovskii
FSBI “Zakusov Institute of Pharmacology”
Russian Federation
Russian Federation
Kryzhanovskiy Sergey A., Dr. Sci. (Med.), Head of laboratory of pharmacological screening
SPIN code: 6596-4865
Moscow
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Review
For citations:
Ionova E.O., Barchukova E.I., Vititnova M.B., Tsorin I.B., Kryzhanovskii S.A. Comparative evaluation of echocardiographic characteristics of the heart left ventricle in female and male rats. Pharmacokinetics and Pharmacodynamics. 2021;(1):14-17. (In Russ.) https://doi.org/10.37489/2587-7836-2021-1-14-17
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