phkineticaФармакокинетика и ФармакодинамикаPharmacokinetics and Pharmacodynamics2587-78362686-8830ООО «Издательство ОКИ»phkinetica-156Research ArticleАКТУАЛЬНЫЙ ОБЗОРCURRENT REVIEWSФакторы, влияющие на биологическую доступность лекарственных препаратовFactors, effecting on drug bioavailabilityБочковП. О.BochkovP. .noemail@neicon.ruШевченкоР. В.ShevchenkoR. .noemail@neicon.ruЛитвинА. А.LitvinA. .noemail@neicon.ruКолывановГ. Б.KolyvanovG. .noemail@neicon.ruЖердевВладимир ПавловичZherdevV. .zherdevpharm@mail.ruФГБНУ «НИИ фармакологии имени В.В. Закусова»РоссияFSBSI «Zakusov Institute of Pharmacology»Russian Federation201609042020011220Copyright © Бочков П.О., Шевченко Р.В., Литвин А.А., Колыванов Г.Б., Жердев В.П., 20202020Бочков П.О., Шевченко Р.В., Литвин А.А., Колыванов Г.Б., Жердев В.П.Bochkov P..., Shevchenko R..., Litvin A..., Kolyvanov G..., Zherdev V...Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.pharmacokinetica.ru/jour/article/view/156

Рассматривается влияние таких факторов, как вспомогательное вещество, тип и общий физико-химический характер лекарственной формы, некоторые технологические приемы производства лекарственных форм на биологическую доступность лекарственных препаратов. Влияние перечисленных факторов рассмотрено на примерах препаратов, используемых в медицинской практике.

Effects such as excipients, type and general physico-chemical properties of drug form, some of technological manufacturing approaches of the drug forms on bioavailability were consider. Effects of the above-listed factors on the examples used in medical practice were demonstrated.

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The authors declare that there are no conflicts of interest present.